Gal Manella

Congratulations to Gal Manella, Zuckerman Israeli Postdoctoral Scholar at California Institute of Technology, on publishing “Steroid hormone receptors through Cry2 are key players in the circadian clock response to serum” in Nature Communications. Dr.  Manella and his colleages found that  circulating signals synchronize cellular circadian clocks, the internal timers that coordinate biological processes with daily cycles.

Abstract
Circadian clocks are cell-autonomous oscillators that are present in most cells of the body and temporally coordinate their function. Alignment of cellular clocks with each other and the environment is mediated mostly through blood borne signals. Although serum is a potent resetting signal for circadian clocks, the underlying intracellular molecular underpinnings are largely unknown.